Silodosin with DutasterideSILOZOR D8 TABLET

Silozor D8 combines Silodosin, a selective α1A-adrenergic receptor antagonist, and Dutasteride,
a dual 5α-reductase inhibitor, for comprehensive management of LUTS due to Benign Prostatic Hyperplasia (BPH)
in adults, regardless of prostate size. Silodosin relaxes smooth muscle in the bladder neck, prostate,
and urethra, improving urinary flow and relieving obstruction. Dutasteride blocks the conversion of
testosterone to dihydroxy-testosterone (DHT), the key driver of prostatic enlargement, resulting in
significant reduction in prostate volume and serum Prostate Specific Antigen (PSA) levels. Silozor D8
helps prevent acute urinary retention and reduces the need for BPH-related surgery. It is free from blood
pressure-related side effects and is well tolerated with long-term use, making it a safe and effective choice,
even in hypertensive patients.

• Dosage:Once daily OR as directed by the physician
• Form: Tablet
• Indications:
  1. Benign Prostatic Hyperplasia
  2. Lower Urinary Tract Symptoms
  3. Acute Urinary Retention
• Composition: Silodosin 8 mg + Dutasteride 0.5 mg
• Mode of Action: Silozor D8 combines Silodosin, a highly selective α1A-adrenergic receptor antagonist (targeting ~75% of receptors in the lower urinary tract), and Dutasteride, a dual 5α-reductase inhibitor, for effective management of LUTS due to BPH. Silodosin relaxes smooth muscles in the prostate, bladder neck, and urethra, reducing intra-urethral pressure and easing symptoms like hesitancy, dribbling, painful urination, and incomplete emptying. Dutasteride inhibits testosterone-to-DHT conversion, preventing further prostate enlargement. Clinically proven to be safe for hypertensive patients, Silozor D8 offers long-term symptom relief without cardiac side effects.
• Packaging:10*1*10’S
• Therapy Area: Urological medicine